Quantifying CDK inhibitor selectivity in live cells

Congratulations to our friends at Promega & SGC-UNC who have developed a platform to comprehensively study CDK inhibitor target engagement across the whole family in live cells. Very excited we could contribute - check out the full paper now published in Nature Communications:

https://www.nature.com/articles/s41467-020-16559-0

#chemicalprobes #targetengagement #drugdiscovery #CDK