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Re-Evaluating the Mechanism of Action of α,β-Unsaturated Carbonyl DUB Inhibitors b-AP15 and VLX1570:

Congratulations to Jenny & Adan on their work on covalent inhibitors of DUBs now published in J. Med. Chem.



This has been a great collaboration between the labs of Ed Tate, Benedict Kessler, Olivier Feron, and the Huber group.


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Two open postdoc positions available!

We are looking for two enthusiastic postdoctoral fellows with expertise in structural biology to join us in our effort to study the function of proteins involved in #ubiquitination & #RNAmetabolism -

Open PostDoc position!

Great news: we have an open position for a PostDoc in structural biology/ biochemisrty. We would love to welcome you to our team, please apply here.

Congratulations!

Congratulations to Ruth, @MonikaGullerova & team on their new paper @CellReports showing how RNA transcribed during DSB repair disrupts the interaction between TIRR (NUDT16L1) and 53BP1! Glad we could

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