Re-Evaluating the Mechanism of Action of α,β-Unsaturated Carbonyl DUB Inhibitors b-AP15 and VLX1570:

Congratulations to Jenny & Adan on their work on covalent inhibitors of DUBs now published in J. Med. Chem.


https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00144


This has been a great collaboration between the labs of Ed Tate, Benedict Kessler, Olivier Feron, and the Huber group.


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©2019 by Huber Lab.