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    Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

    Just out in Nature Chemical Biology!


    https://www.nature.com/articles/s41589-019-0310-x


    Congratulations to the team at Boehringer Ingelheim and SGC Toronto!

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    Quantifying CDK inhibitor selectivity in live cells

    Re-Evaluating the Mechanism of Action of α,β-Unsaturated Carbonyl DUB Inhibitors b-AP15 and VLX1570:

    In the Pipeline – Covalent Fragments & Inhibitors

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