Check out this blog post by industry expert Derek Lowe summarising his thoughts on covalent fragments & inhibitors which mentions some of our own recent work using crystallographic and covalent fragment screens in collaboration with the London and Brennan labs (https://pubs.acs.org/doi/10.1021/jacs.9b02822).
We are looking for two enthusiastic postdoctoral fellows with expertise in structural biology to join us in our effort to study the function of proteins involved in #ubiquitination & #RNAmetabolism -
Great news: we have an open position for a PostDoc in structural biology/ biochemisrty. We would love to welcome you to our team, please apply here.
Congratulations to Ruth, @MonikaGullerova & team on their new paper @CellReports showing how RNA transcribed during DSB repair disrupts the interaction between TIRR (NUDT16L1) and 53BP1! Glad we could