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NEWS

Congratulations to Jenny & Adan on their work on covalent inhibitors of DUBs now published in J. Med. Chem.


https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00144


This has been a great collaboration between the labs of Ed Tate, Benedict Kessler, Olivier Feron, and the Huber group.




Check out this blog post by industry expert Derek Lowe summarising his thoughts on covalent fragments & inhibitors which mentions some of our own recent work using crystallographic and covalent fragment screens in collaboration with the London and Brennan labs (https://pubs.acs.org/doi/10.1021/jacs.9b02822).

Many thanks to MyelomaUK for their generous support and hosting our Freed foundation fellow Felix who is working on new approaches to characterise drug responses in multiple myeloma.


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