Target Identification & Validation in Drug Discovery

What makes a good drug target? Technology Networks has recently featured an article highlighting some of the challenges that the Huber Lab aims to tackle.

Dr Kilian V. M. Huber states,"A good drug target needs to be relevant to the disease phenotype and should be amenable to therapeutic modulation. At the same time, you need to have a good therapeutic window to assure that any therapeutic modality aimed at the target will not cause side effects by disrupting the physiological function of the target in healthy tissue."

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